" /> nucleic acid denaturation - CISMeF





Preferred Label : nucleic acid denaturation;

MeSH definition : Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is melted by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.;

MeSH synonym : acid denaturation, nucleic; nucleic acid denaturations; denaturation, nucleic acid;

MeSH hyponym : RNA denaturation; DNA denaturation; Denaturation, RNA; Denaturation, DNA; DNA Melting;

MeSH annotation : IM general only; coord NIM with DNA or RNA or specific (IM);

Wikipedia link : https://en.wikipedia.org/wiki/Dna melting;

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Keyword's position in hierarchy(ies) : arborescence

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Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is melted by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.

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26/04/2025


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