nomifensine - CISMeF

Preferred Label : nomifensine;

MeSH definition : An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266);

MeSH synonym : nomifensin; linamiphen;

CISMeF synonym : 32795-47-4 (Nomifensine maleate);

MeSH hyponym : Hoe-984; merital; Nomifensine Maleate; Maleate, Nomifensine; Nomifensine Maleate (1:1); Hoe 984; Hoe984;

MeSH CAS label : 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-;

MeSH Related Number : nomifensine maleate; 24526-64-5 (Nomifensine); 32795-47-4 (maleate (1:1)); 76S8CUH5MR;

Registry Number MeSH : 24526-64-5;

Related CAS MeSH : 76S8CUH5MR (Nomifensine maleate);

Wikipedia link : https://en.wikipedia.org/wiki/Merital;

Is substance : O;

UNII : 1LGS5JRP31;

InChIKey : XXPANQJNYNUNES-UHFFFAOYSA-N;

Details

Origin ID

D009627;

UMLS CUI

C0028277;

ATC code(s)
- nomifensine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 8-ammonio-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinolinium maleate [Substance BNPC]
- Nomifensine [ICHI extension code]
Currated CISMeF NLP mapping
- Nomifensine [ICD-11 Extension code]
- Nomifensine [LOINC component]
- Nomifensine [NCIt concept]
- Nomifensine (substance) [SNOMED CT concept]
Pharmacological action(s)
- dopamine uptake inhibitors [MeSH Descriptor]
Record concept(s)
- Hoe-984 [MeSH concept]
- Nomifensine Maleate [MeSH concept]
- merital [MeSH concept]
- nomifensine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3',4'-dihydroxynomifensine [MeSH Supplementary Concept]
- 3'-hydroxy-4'-methoxynomifensine [MeSH Supplementary Concept]
- 4'-hydroxy-3'-methoxynomifensine [MeSH Supplementary Concept]
- 4'-hydroxynomifensine [MeSH Supplementary Concept]
- 4-hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline [MeSH Supplementary Concept]
- psyton [MeSH Supplementary Concept]
See also inter- (CISMeF)
- 8-ammonio-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinolinium maleate [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nomifensine [ICD-11 Extension code]
- Nomifensine [NCIt concept]
- Nomifensine [LOINC component]
- Nomifensine (substance) [SNOMED CT concept]
- nomifensine [ATC Code]
Validated automatic mappings to BTNT
- Nomifensine Maleate [NCIt concept]
- nomifensine [ATC Code]

Keyword's position in hierarchy(ies) :

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