Preferred Label : myosins;
MeSH definition : A diverse superfamily of proteins that function as translocating proteins. They share
the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins
generally consist of heavy chains which are involved in locomotion, and light chains
which are involved in regulation. Within the structure of myosin heavy chain are three
domains: the head, the neck and the tail. The head region of the heavy chain contains
the actin binding domain and MgATPase domain which provides energy for locomotion.
The neck region is involved in binding the light-chains. The tail region provides
the anchoring point that maintains the position of the heavy chain. The superfamily
of myosins is organized into structural classes based upon the type and arrangement
of the subunits they contain.;
MeSH synonym : actin activated atpase; atpase, actin activated; myosin; atpase, myosin; adenosinetriphosphatase, myosin; myosin atpase; myosin adenosinetriphosphatase; actin-activated atpase; atpase, actin-activated; adenosine triphosphatase, myosin; myosin adenosine triphosphatase;
CISMeF synonym : EC 3.6.1.4;
Related MeSH term : actomyosin adenosinetriphosphatase; Adenosinetriphosphatase, Actomyosin; ATPase, Actomyosin; Actomyosin ATPase;
MeSH Related Number : actomyosin adenosinetriphosphatase; EC 3.6.4.1;
Registry Number MeSH : EC 3.6.4.1;
Related CAS MeSH : EC 3.6.1.- (Actomyosin adenosinetriphosphatase);
MeSH annotation : GEN or unspecified; prefer specifics; general or unspecified; prefer specifics;
Wikipedia link : https://en.wikipedia.org/wiki/Myosin;
Related CISMeF synonym : EC 3.6.1.-;
Is substance : O;
UNII : EC 3.6.4.1;
Origin ID : D009218;
UMLS CUI : C0027096;
Allowable qualifiers
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A diverse superfamily of proteins that function as translocating proteins. They share
the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins
generally consist of heavy chains which are involved in locomotion, and light chains
which are involved in regulation. Within the structure of myosin heavy chain are three
domains: the head, the neck and the tail. The head region of the heavy chain contains
the actin binding domain and MgATPase domain which provides energy for locomotion.
The neck region is involved in binding the light-chains. The tail region provides
the anchoring point that maintains the position of the heavy chain. The superfamily
of myosins is organized into structural classes based upon the type and arrangement
of the subunits they contain.
