muscimol - CISMeF

Preferred Label : muscimol;

MeSH definition : A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.;

MeSH synonym : pantherine; agarin;

CISMeF synonym : 5-(aminomethyl)isoxazol-3-ol hydrate;

MeSH CAS label : 3(2H)-Isoxazolone, 5-(aminomethyl)-;

Registry Number MeSH : 2763-96-4;

Wikipedia link : https://en.wikipedia.org/wiki/Muscimol;

Codes EINECS : 220-430-4;

Is substance : O;

Details

Origin ID

D009118;

UMLS CUI

C0026818;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 5-(aminomethyl)isoxazol-3-ol hydrate [Substance BNPC]
Pharmacological action(s)
- GABA agents [MeSH Descriptor]
- GABA-A receptor agonists [MeSH Descriptor]
Record concept(s)
- muscimol [MeSH concept]
Related MeSH Supplementary Concept(s)
- N,N-dimethylmuscimol [MeSH Supplementary Concept]
- N,N-dimethylthiomuscimol [MeSH Supplementary Concept]
- N-methylmuscimol [MeSH Supplementary Concept]
- dihydromuscimol [MeSH Supplementary Concept]
- isomuscimol [MeSH Supplementary Concept]
- thiomuscimol [MeSH Supplementary Concept]
See also
- receptors, GABA-A [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 5-(aminomethyl)isoxazol-3-ol hydrate [Substance BNPC]
- Muscimol (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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