MeSH definition : Genetic loci responsible for the encoding of histocompatibility antigens other than
those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. The antigens encoded by these
genes are often responsible for graft rejection in cases where histocompatibility
has been established by standard tests. The location of some of these loci on the
X and Y chromosomes explains why grafts from males to females may be rejected while
grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility
loci have been recognized, comprising more than 500 genes.;
MeSH synonym : histocompatibility loci, minor; loci, minor histocompatibility; minor histocompatibility locus; histocompatibility locus, minor; locus, minor histocompatibility;
Genetic loci responsible for the encoding of histocompatibility antigens other than
those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. The antigens encoded by these
genes are often responsible for graft rejection in cases where histocompatibility
has been established by standard tests. The location of some of these loci on the
X and Y chromosomes explains why grafts from males to females may be rejected while
grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility
loci have been recognized, comprising more than 500 genes.