Methylmalonyl-CoA mutase

Preferred Label : Methylmalonyl-CoA mutase;

MeSH definition : An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. EC 5.4.99.2.;

MeSH synonym : mutase, methylmalonyl-coa; isomerase, methylmalonyl-coa; methylmalonyl coa isomerase; methylmalonyl-coa isomerase; methylmalonyl CoA mutase;

MeSH CAS label : (R)-2-Methyl-3-oxopropanoyl-CoA CoA-carbonylmutase;

MeSH Related Number : 9023-90-9 (CAS RN);

Registry Number MeSH : EC 5.4.99.2;

MeSH annotation : /defic: consider also METHYLMALONIC ACID /urine (IM) AMINO ACID METABOLISM, INBORN ERRORS (IM);

Wikipedia link : https://en.wikipedia.org/wiki/Methylmalonyl-coa mutase;

Is substance : O;

UNII : EC 5.4.99.2;

Details

Origin ID

D008765;

UMLS CUI

C0025789;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Methylmalonyl CoA mutase [LOINC component]
- Methylmalonyl-coenzyme A mutase (substance) [SNOMED CT concept]
- methylmalonyl-coa mutase [SNOMED Notion]
Indexing information
- 3-carboxypropyl-coenzyme A [MeSH Supplementary Concept]
Record concept(s)
- Methylmalonyl-CoA mutase [MeSH concept]
Related MeSH Supplementary Concept(s)
- Methylmalonyl-Coenzyme A mutase deficiency [MeSH Supplementary Concept]
- methylmalonic aciduria due to Methylmalonyl-CoA mutase deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Methylmalonyl CoA mutase [LOINC component]
- Methylmalonyl-coenzyme A mutase (substance) [SNOMED CT concept]
- methylmalonyl-coa mutase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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