procollagen-lysine, 2-oxoglutarate 5-dioxygenase

Preferred Label : procollagen-lysine, 2-oxoglutarate 5-dioxygenase;

MeSH definition : A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.;

MeSH synonym : collagen lysyl hydroxylase; dioxygenase, lysine 2-oxoglutarate; hydroxylase, collagen lysyl; hydroxylase, lysine; hydroxylase, lysyl; hydroxylase, protocollagen lysyl; lysine hydroxylase; lysine 2 oxoglutarate dioxygenase; lysine 2-oxoglutarate dioxygenase; lysyl hydroxylase; protocollagen lysyl hydroxylase; 2-oxoglutarate dioxygenase, lysine; 2-oxoglutarate 5-dioxygenase procollagen-lysine; 5-dioxygenase procollagen-lysine, 2-oxoglutarate; procollagen lysine, 2 oxoglutarate 5 dioxygenase;

MeSH CAS label : Procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating);

Registry Number MeSH : EC 1.14.11.4;

MeSH annotation : DF: note short X ref;

Is substance : O;

UNII : EC 1.14.11.4;

Details

Origin ID

D008240;

UMLS CUI

C0024341;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Procollagen-lysine, 2-oxoglutarate 5-dioxygenase [OMIM gene]
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase (substance) [SNOMED CT concept]
- procollagen-lysine 5-dioxygenase activity [GO term]
- procollagen-lysine,2-oxoglutarate 5-dioxygenase [SNOMED Notion]
Record concept(s)
- Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- JMJD4 protein, mouse [MeSH Supplementary Concept]
- PLOD1 protein, human [MeSH Supplementary Concept]
- PLOD2 protein, human [MeSH Supplementary Concept]
- PLOD3 protein, human [MeSH Supplementary Concept]
- Plod2 protein, rat [MeSH Supplementary Concept]
- bone fragility with contractures, arterial rupture, and deafness [MeSH Supplementary Concept]
- lysyl hydroxylase 1, human [MeSH Supplementary Concept]
- lysyl hydroxylase 1, zebrafish [MeSH Supplementary Concept]
- lysyl hydroxylase 2, mouse [MeSH Supplementary Concept]
- lysyl hydroxylase 2, zebrafish [MeSH Supplementary Concept]
- lysyl hydroxylase 3, mouse [MeSH Supplementary Concept]
- plod3 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Procollagen-lysine,2-oxoglutarate 5-dioxygenase (substance) [SNOMED CT concept]
- procollagen-lysine,2-oxoglutarate 5-dioxygenase [SNOMED Notion]

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