kainic acid - CISMeF

Preferred Label : kainic acid;

MeSH definition : (2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.;

MeSH synonym : digenic acid; acid, kainic; acid, digenic;

MeSH hyponym : kainate;

MeSH CAS label : 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-;

MeSH Related Number : 487-79-6 (Kainic acid);

Registry Number MeSH : 487-79-6;

MeSH annotation : an antinematodal agent & excitatory amino acid agonist;

Wikipedia link : https://en.wikipedia.org/wiki/Kainic acid;

Is substance : O;

UNII : SIV03811UC;

InChIKey : VLSMHEGGTFMBBZ-OOZYFLPDSA-N;

Details

Origin ID

D007608;

UMLS CUI

C0022471;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Kainic Acid [NCIt concept]
Indexing information
- 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid [MeSH Supplementary Concept]
Pharmacological action(s)
- antinematodal agents [MeSH Descriptor]
- excitatory amino acid agonists [MeSH Descriptor]
- neurotransmitter agents [MeSH Descriptor]
Record concept(s)
- kainate [MeSH concept]
- kainic acid [MeSH concept]
Related MeSH Supplementary Concept(s)
- (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid [MeSH Supplementary Concept]
- 1'-hydroxykainic acid [MeSH Supplementary Concept]
- 2-carboxy-4-(1-phenylethen-1-yl)pyrrolidine-3-acetic acid [MeSH Supplementary Concept]
- 4-(1-(4-azidobenzamidomethyl)ethenyl)-2-carboxypyrrolidin-3-ylacetic acid [MeSH Supplementary Concept]
- 4-(2-hydroxyphenyl)-2-carboxy-3-pyrrolidineacetic acid [MeSH Supplementary Concept]
- 4-(2-methoxyphenyl)-2-carboxy-3-pyrrolidineacetic acid [MeSH Supplementary Concept]
- acromelic acid A [MeSH Supplementary Concept]
- acromelic acid B [MeSH Supplementary Concept]
- allokainic acid [MeSH Supplementary Concept]
- alpha-ketokainic acid [MeSH Supplementary Concept]
- carboxy-2-nitrobenzyl kainate [MeSH Supplementary Concept]
- dihydrokainic acid [MeSH Supplementary Concept]
- domoic acid [MeSH Supplementary Concept]
- kainic acid diethyl ester [MeSH Supplementary Concept]
- kainylaminooxyacetylglycine [MeSH Supplementary Concept]
- methoxyphenylkainic acid [MeSH Supplementary Concept]
- phenylkainic acid [MeSH Supplementary Concept]
See also
- receptors, kainic acid [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Kainic Acid [NCIt concept]

Keyword's position in hierarchy(ies) :

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