MeSH definition : A 15 kD joining peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN
A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one
J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the
polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary
for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING
REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light
and heavy chains.; A 15 kDa joining peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN
A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one
J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the
polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary
for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING
REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light
and heavy chains.;
A 15 kD joining peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN
A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one
J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the
polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary
for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING
REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light
and heavy chains. A 15 kDa joining peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN
A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one
J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the
polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary
for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING
REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light
and heavy chains.