Preferred Label : immunoglobulin gamma-chains;
MeSH definition : Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa.
They contain about 450 amino acid residues arranged in four domains and an oligosaccharide
component covalently bound to the Fc fragment constant region. The gamma heavy chain
subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G
isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than
the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.;
MeSH synonym : gamma-chain, immunoglobulin; gamma chain immunoglobulins; gamma-chains, immunoglobulin; immunoglobulin gamma-chain; immunoglobulin gamma chain; immunoglobulins, gamma-chain; immunoglobulins, gamma chain; gamma-chain immunoglobulins; gamma immunoglobulin heavy chain; gamma immunoglobulin heavy chains; immunoglobulin gamma chains;
MeSH hyponym : gamma-2a-Immunoglobulin heavy chain; gamma-1-Immunoglobulin heavy chain; gamma-2b-Immunoglobulin heavy chain; Heavy Chain, gamma-2a-Immunoglobulin; gamma 2a Immunoglobulin Heavy Chain; Heavy Chain, gamma-2b-Immunoglobulin; gamma 2b Immunoglobulin Heavy Chain; Heavy Chain, gamma-1-Immunoglobulin; gamma 1 Immunoglobulin Heavy Chain;
MeSH annotation : gammopathy: coordinate IMMUNOGLOBULIN GAMMA-CHAINS (IM) with PARAPROTEINEMIAS (IM)
but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow
text; DF: IG GAMMA CHAIN;
Is substance : O;
Origin ID : D007142;
UMLS CUI : C0021033;
Allowable qualifiers
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
Semantic type(s)
UMLS correspondences (same concept)
Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa.
They contain about 450 amino acid residues arranged in four domains and an oligosaccharide
component covalently bound to the Fc fragment constant region. The gamma heavy chain
subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G
isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than
the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.