immunoglobulin variable region

Preferred Label : immunoglobulin variable region;

MeSH definition : That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.;

MeSH synonym : immunoglobulin v; variable region, immunoglobulin; variable regions, immunoglobulin; variable region, ig; immunoglobulin variable regions; regions, immunoglobulin variable; ig variable region; ig variable regions; variable regions, ig;

MeSH hyponym : framework region, immunoglobulin; Framework Regions, Immunoglobulin; Immunoglobulin Framework Regions; Ig Framework Region; Framework Region, Ig; Framework Regions, Ig; Ig Framework Regions; Immunoglobulin Framework Region;

Related MeSH term : immunoglobulin fv fragments; Fragment, Immunoglobulin Fv; Fragments, Immunoglobulin Fv; Fv Fragment, Immunoglobulin; Fv Fragments, Immunoglobulin; Immunoglobulin Fv Fragment; Fv Antibody Fragments; Antibody Fragment, Fv; Antibody Fragments, Fv; Fragment, Fv Antibody; Fragments, Fv Antibody; Fv Antibody Fragment; Fv Fragments; Fragment, Fv; Fragments, Fv; Fv Fragment;

MeSH annotation : DF: IG VARIABLE REGION;

Is substance : O;

Details

Origin ID

D007135;

UMLS CUI

C0877857;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Antibacterial monoclonal antibodies [ATC Code]
- IgM [MedDRA LLT]
- Immunoglobulin [NCIt concept]
- Immunoglobulin [ICD-10 Sub-category (who)]
- Immunoglobulin [FMA entity]
- Immunoglobulin part (substance) [SNOMED CT concept]
- Immunoglobulins [MedDRA Preferred Term]
- antigen binding [GO term]
- immunoglobulin [ICPS Descriptor]
- immunoglobulin, nos [SNOMED Notion]
- immunoglobulins [ATC Code]
- immunoglobulins, e [Substance BNPC]
Currated CISMeF NLP mapping
- Immunoglobulin Variable Region [NCIt concept]
- Immunoglobulin, variable region (substance) [SNOMED CT concept]
- antibody variable region [SNOMED Notion]
- immunoglobulin, variable region [SNOMED Notion]
False automatic mappings
- Immunoglobulin (substance) [SNOMED CT concept]
Indexing information
- CD40LIg fusion protein [MeSH Supplementary Concept]
- IL-15-Fcgamma2a protein, human [MeSH Supplementary Concept]
- anti-quadruplex DNA scFv [MeSH Supplementary Concept]
- immunocorticotropin [MeSH Supplementary Concept]
- immunoglobulin fv [MeSH Supplementary Concept]
- scFvC54-sTRAIL fusion protein [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- framework region, immunoglobulin [MeSH concept]
- immunoglobulin fv fragments [MeSH concept]
- immunoglobulin variable region [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1D4.1-325 DVD-Ig protein [MeSH Supplementary Concept]
- ID 32-44 [MeSH Supplementary Concept]
- LMB-11 [MeSH Supplementary Concept]
See also
- Immunoglobulin Domains [MeSH Descriptor]
- binding sites, antibody [MeSH Descriptor]
- gene rearrangement [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Immunoglobulin Variable Region [NCIt concept]
- Immunoglobulin, variable region (substance) [SNOMED CT concept]
- antibody variable region [SNOMED Notion]
- immunoglobulin, variable region [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients