" /> immunoglobulin joining region - CISMeF





Preferred Label : immunoglobulin joining region;

MeSH definition : A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.;

MeSH synonym : ig joining region; joining region, immunoglobulin; joining region, ig;

Related MeSH term : immunoglobulin joining region peptide fragments;

MeSH annotation : DF: IG JOINING REGION;

Is substance : O;

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Keyword's position in hierarchy(ies) : arborescence

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A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

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02/05/2025


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