MeSH definition : The secretion of histamine from mast cell and basophil granules by exocytosis. This
can be initiated by a number of factors, all of which involve binding of IgE, cross-linked
by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine
binds to a number of different target cell receptors and exerts a wide variety of
effects.;
The secretion of histamine from mast cell and basophil granules by exocytosis. This
can be initiated by a number of factors, all of which involve binding of IgE, cross-linked
by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine
binds to a number of different target cell receptors and exerts a wide variety of
effects.