glaucarubin - CISMeF

Preferred Label : glaucarubin;

MeSH definition : (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.;

MeSH synonym : kirondrin;

MeSH CAS label : Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,2alpha,11beta,12alpha,15beta(S))-;

MeSH Related Number : 1448-23-3 (Glaucarubin);

Registry Number MeSH : 1448-23-3;

Is substance : O;

UNII : EH6H7VS52J;

InChIKey : LZKVXMYVBSNXER-YZPKDWIXSA-N;

Details

Origin ID

D005900;

UMLS CUI

C0017600;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Glaucarubin [ICHI extension code]
Currated CISMeF NLP mapping
- Glaucarubin [ICD-11 Extension code]
- Glaucarubin [NCIt concept]
- Glaucarubin (substance) [SNOMED CT concept]
- glaucarubin [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents, phytogenic [MeSH Descriptor]
Record concept(s)
- glaucarubin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 13,18-dehydroglaucarubinone [MeSH Supplementary Concept]
- glaucarubinone [MeSH Supplementary Concept]
- glaucarubolone [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Glaucarubin [ICD-11 Extension code]
- Glaucarubin [NCIt concept]
- Glaucarubin (substance) [SNOMED CT concept]
- glaucarubin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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