galactosylceramidase

Preferred Label : galactosylceramidase;

MeSH definition : An enzyme that hydrolyzes galactose from ceramide monohexosides. Deficiency of this enzyme may cause globoid cell leukodystrophy (LEUKODYSTROPHY, GLOBOID CELL). EC 3.2.1.46.;

MeSH synonym : beta-galactosidase, galactosylcerebroside; galactosylceramide galactosidase; galactosidase, galactosylceramide; galactocerebrosidase; galactosylceramide beta-galactosidase; galactosylcerebroside beta-galactosidase; beta-galactosidase, galactosylceramide;

MeSH CAS label : D-Galactosyl-N-acylsphingosine galactohydrolase;

Registry Number MeSH : EC 3.2.1.46;

MeSH annotation : /defic: consider also LEUKODYSTROPHY, GLOBOID CELL;

Wikipedia link : https://en.wikipedia.org/wiki/Galactosylceramidase;

Is substance : O;

UNII : EC 3.2.1.46;

Details

Origin ID

D005698;

UMLS CUI

C0016957;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 2-(2'-hydroxydodecanoyl)amino-1-phenyl-1,3-propanediol [MeSH Supplementary Concept]
- PSAP protein, human [MeSH Supplementary Concept]
Record concept(s)
- galactosylceramidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- galactosylsphingosine (psychosine) beta-galactosidase [MeSH Supplementary Concept]
- lactosylceramidase [MeSH Supplementary Concept]
See also
- leukodystrophy, globoid cell [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Galactocerebrosidase [LOINC component]
- Galactosylceramidase [LOINC component]
- Galactosylceramidase (substance) [SNOMED CT concept]
- galactosylceramidase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients