colforsin - CISMeF

Preferred Label : colforsin;

MeSH definition : Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.;

MeSH synonym : coleonol; forskolin; N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl ester HCl;

MeSH hyponym : NKH 477; NKH-477; NKH477;

MeSH CAS label : 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-;

MeSH Related Number : 138605-00-2 (Colforsin); 66428-89-5 (Forskolin);

Registry Number MeSH : 66428-89-5;

Wikipedia link : https://en.wikipedia.org/wiki/Forskolin;

Is substance : O;

UNII : 1F7A44V6OU;

InChIKey : OHCQJHSOBUTRHG-KGGHGJDLSA-N;

Details

Origin ID

D005576;

UMLS CUI

C0917964;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Colforsin [NCIt concept]
Pharmacological action(s)
- adjuvants, immunologic [MeSH Descriptor]
- bronchodilator agents [MeSH Descriptor]
- cardiotonic agents [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- NKH 477 [MeSH concept]
- colforsin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,9-dideoxyforskolin [MeSH Supplementary Concept]
- 1-acetyl-7-deacetylforskolin [MeSH Supplementary Concept]
- 14,15-dihydroforskolin [MeSH Supplementary Concept]
- 2-(3-(4-hydroxy-3-iodophenyl)propionamido)-N-ethyl-7-(aminocarbonyl)-7-desacetylforskolin [MeSH Supplementary Concept]
- 3'-iodo-4'-azidosalicylamidoethylamido-7-succinyldeacetylforskolin [MeSH Supplementary Concept]
- 3-(3-iodo-4-hydroxyphenyl)propionamide derivative of 6-(2-aminoethyl)aminocarbonylforskolin [MeSH Supplementary Concept]
- 3-iodo-4-azidophenethylamido-7-O-succinyldeacetylforskolin [MeSH Supplementary Concept]
- 6-((piperidino)acetoxy)-7-desacetylforskolin [MeSH Supplementary Concept]
- 7-bromoacetyl-7-desacetylforskolin [MeSH Supplementary Concept]
- 7-deacetyl-6-(N-acetylglycyl)forskolin [MeSH Supplementary Concept]
- 7-desacetyl-7-(O-propionyl)hydroxyaminocarbonylforskolin [MeSH Supplementary Concept]
- 7-desacetyl-7-aminoethylaminocarbonyl forskolin [MeSH Supplementary Concept]
- 7-desacetylforskolin [MeSH Supplementary Concept]
- 7-forskolinyl-2-(3-azido-5-hydroxy-4-iodophenoxy)acetate [MeSH Supplementary Concept]
- 7-tosyl-7-desacetylforskolin [MeSH Supplementary Concept]
- 7b-deacetyl-7b-(gamma-(morpholino)butyryl)forskolin [MeSH Supplementary Concept]
- L 858051 [MeSH Supplementary Concept]
- N-(3-(4-azido-3-iodophenyl)-propionamide)-7-aminoethylcarbamyl-7-desacetylforskolin [MeSH Supplementary Concept]
- N-(3-(4-azido-3-iodophenyl)propionamide)-6-aminoethylcarbamylforskolin [MeSH Supplementary Concept]
- colforsin daropate [MeSH Supplementary Concept]
- forskolin-agarose [MeSH Supplementary Concept]
- spiroforskolin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Colforsin [NCIt concept]

Keyword's position in hierarchy(ies) :

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