filipin - CISMeF

Preferred Label : filipin;

MeSH definition : A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.;

MeSH synonym : desoxylagosin; filimarisin; filipin III;

MeSH hyponym : U-5956; NSC-3364; NSC 3364; NSC3364; U 5956; U5956;

Related MeSH term : filipin I; filipin IV; filipin II;

MeSH Related Number : 480-49-9 (Filipin);

Registry Number MeSH : 480-49-9;

Wikipedia link : https://en.wikipedia.org/wiki/Filipin;

Is substance : O;

UNII : 87Z59R7D14;

InChIKey : IMQSIXYSKPIGPD-IUIVKZSISA-N;

Details

Origin ID

D005372;

UMLS CUI

C0016095;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Filipin [SMS substance]
- Filipin III [NCIt concept]
Pharmacological action(s)
- anti-bacterial agents [MeSH Descriptor]
- antifungal agents [MeSH Descriptor]
- antiviral agents [MeSH Descriptor]
Record concept(s)
- NSC-3364 [MeSH concept]
- U-5956 [MeSH concept]
- filipin [MeSH concept]
- filipin I [MeSH concept]
- filipin II [MeSH concept]
- filipin IV [MeSH concept]
Related MeSH Supplementary Concept(s)
- 32,33-didehydroroflamycoin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Filipin III [NCIt concept]

Keyword's position in hierarchy(ies) :

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