Preferred Label : exfoliatins;
MeSH definition : Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal
necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause
a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative
disease, toxic epidermal necrolysis, etc.;
MeSH synonym : staphylococcal exfoliative toxin; exfoliative toxin, staphylococcal; toxin, staphylococcal exfoliative; epidermolysins;
CISMeF synonym : A, exfoliatin toxin; B, exfoliative toxin;
MeSH Hyperonym : epidermolytic toxins; exfoliative toxins; Toxins, Exfoliative; Toxins, Epidermolytic;
MeSH hyponym : exfoliative toxin B; exfoliatin toxin A; Toxin A, Exfoliatin; Toxin B, Exfoliative;
Related MeSH term : dermolysins;
MeSH annotation : /antag permitted but consider also ANTITOXINS;
Is substance : O;
Origin ID : D005083;
UMLS CUI : C0015266;
Allowable qualifiers
- False automatic mappings
- Pharmacological action(s)
- Record concept(s)
- Semantic type(s)
Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal
necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause
a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative
disease, toxic epidermal necrolysis, etc.
