Preferred Label : ethacrynic acid;
MeSH definition : A compound that inhibits symport of sodium, potassium, and chloride primarily in the
ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological
action results in excretion of these ions, increased urinary output, and reduction
in extracellular fluid. This compound has been classified as a loop or high ceiling
diuretic.;
MeSH synonym : acid, etacrynic; acid, ethacrinic; ethacrinic acid; acid, ethacrynic; etacrynic acid;
MeSH hyponym : hydromedin; edecrin; ethacrynate sodium; Sodium, Ethacrynate; Ethacrynic Acid, Sodium Salt;
MeSH CAS label : acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-;
MeSH Related Number : ethacrynate sodium; 58-54-8 (Ethacrynic acid); 6500-81-8 (Na salt); K41MYV7MPM;
Registry Number MeSH : 58-54-8;
Related CAS MeSH : K41MYV7MPM (Ethacrynate sodium);
Wikipedia link : https://en.wikipedia.org/wiki/Etacrynic acid;
Codes EINECS : 200-384-1;
Is substance : O;
UNII : M5DP350VZV;
InChIKey : AVOLMBLBETYQHX-UHFFFAOYSA-N;
Origin ID : D004976;
UMLS CUI : C0014963;
ATC code(s)
- Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- SA12590 [MeSH Supplementary Concept]
- SA9000 [MeSH Supplementary Concept]
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
A compound that inhibits symport of sodium, potassium, and chloride primarily in the
ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological
action results in excretion of these ions, increased urinary output, and reduction
in extracellular fluid. This compound has been classified as a loop or high ceiling
diuretic.
