Preferred Label : DNA helicases;
MeSH definition : Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively
to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing
transient opening. In addition DNA helicases are DNA-dependent ATPases that harness
the free energy of ATP hydrolysis to translocate DNA strands.; Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively
to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing
transient opening. In addition, DNA helicases are DNA-dependent ATPases that harness
the free energy of ATP hydrolysis to translocate DNA strands.;
MeSH synonym : helicases, dna; unwinding proteins, dna; dna unwinding proteins; DNA Unwinding Protein; Protein, DNA Unwinding; Unwinding Protein, DNA; DNA Helicase; Helicase, DNA;
CISMeF synonym : EC 3.6.1.- (ATP-Dependent DNA helicases); EC 3.6.1.- (DNA helicase A); EC 3.6.1.- (DNA helicase E); EC 3.6.1.- (DNA helicase II); EC 3.6.1.- (DNA helicase III);
MeSH hyponym : ATP-Dependent DNA helicases; DNA helicase II; DNA helicase III; DNA helicase E; DNA helicase A; ATP Dependent DNA Helicases; DNA Helicases, ATP-Dependent; Helicases, ATP-Dependent DNA; ATP-Dependent DNA Helicase; ATP Dependent DNA Helicase; DNA Helicase, ATP-Dependent; Helicase, ATP-Dependent DNA;
MeSH Related Number : DNA helicase III; DNA helicase E; DNA helicase II; ATP-Dependent DNA helicases; DNA helicase A; EC 3.6.4.12;
Registry Number MeSH : EC 3.6.1.-; EC 3.6.4.-;
Related CAS MeSH : EC 3.6.4.12 (DNA helicase A); EC 3.6.4.12 (DNA helicase II); EC 3.6.4.12 (DNA helicase III); EC 3.6.4.12 (ATP-Dependent DNA helicases); EC 3.6.4.12 (DNA helicase E);
MeSH annotation : do not confuse entry term DNA UNWINDING PROTEINS with DNA UNTWISTING PROTEINS;
Is substance : O;
Origin ID : D004265;
UMLS CUI : C0920283;
Allowable qualifiers
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
Related MeSH Supplementary Concept(s)
See also
Semantic type(s)
UMLS correspondences (same concept)
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively
to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing
transient opening. In addition DNA helicases are DNA-dependent ATPases that harness
the free energy of ATP hydrolysis to translocate DNA strands.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively
to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing
transient opening. In addition, DNA helicases are DNA-dependent ATPases that harness
the free energy of ATP hydrolysis to translocate DNA strands.