dimethylallyltranstransferase

Preferred Label : dimethylallyltranstransferase;

MeSH definition : An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.;

MeSH synonym : Dimethylallyltransferase; synthetase, geranylpyrophosphate; synthetase, nerylpyrophosphate; dolichyl phosphate synthetase; geranylpyrophosphate synthetase; nerylpyrophosphate synthetase; prenyltransferase;

CISMeF synonym : phosphate synthetase, dolichyl; synthetase, dolichyl phosphate; farnesylpyrophosphate synthetase; pyrophosphate synthetase, geranylgeranyl; synthetase, farnesylpyrophosphate; synthetase, geranylgeranyl pyrophosphate;

Related MeSH term : Geranylgeranyl Pyrophosphate Synthetase;

MeSH CAS label : dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyl (trans) transferase;

MeSH Related Number : 9032-79-5 (CAS RN);

Registry Number MeSH : EC 2.5.1.1;

Wikipedia link : https://en.wikipedia.org/wiki/Prenyltransferase;

Is substance : O;

UNII : EC 2.5.1.1;

Details

Origin ID

D004122;

UMLS CUI

C0012408;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Dimethylallyltranstransferase (substance) [SNOMED CT concept]
- dimethylallyltranstransferase [SNOMED Notion]
Indexing information
- 1-fluorononylidene-1,1-bisphosphonic acid [MeSH Supplementary Concept]
- allylaminomethanone-A [MeSH Supplementary Concept]
- phenethylaminomethanone-A [MeSH Supplementary Concept]
Record concept(s)
- Geranylgeranyl Pyrophosphate Synthetase [MeSH concept]
- dimethylallyltranstransferase [MeSH concept]
Related MeSH Supplementary Concept(s)
- (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, sulfolobus solfataricus [MeSH Supplementary Concept]
- 4-hydroxybenzoic acid oligoprenyltransferase, E coli [MeSH Supplementary Concept]
- CdpNPT protein, aspergillus fumigatus [MeSH Supplementary Concept]
- ERG20 protein, S cerevisiae [MeSH Supplementary Concept]
- FtmPT1 protein, aspergillus fumigatus [MeSH Supplementary Concept]
- GGPS1 protein, human [MeSH Supplementary Concept]
- NovQ protein, streptomyces [MeSH Supplementary Concept]
- PLMP protein, mouse [MeSH Supplementary Concept]
- PTAR1 protein, human [MeSH Supplementary Concept]
- QM protein, Drosophila [MeSH Supplementary Concept]
- RER2 protein, S cerevisiae [MeSH Supplementary Concept]
- UBIAD1 protein, human [MeSH Supplementary Concept]
- Ubiad1 protein, mouse [MeSH Supplementary Concept]
- Ubiad1 protein, zebrafish [MeSH Supplementary Concept]
- fumigaclavine C synthase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Dimethylallyltranstransferase (substance) [SNOMED CT concept]
- dimethylallyltranstransferase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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