complement C3b inactivator proteins

Preferred Label : complement C3b inactivator proteins;

MeSH definition : Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.;

MeSH synonym : inactivators, c3b; factors, conglutinogen activating; conglutinogen activating factors; complement 3b inhibitors; complement c3b inhibitor proteins; c3b inactivators; c3b inhibitors; inhibitors, c3b; complement 3b inactivators; inactivators, complement 3b; complement c3b inactivators; inactivators, complement c3b; inhibitors, complement 3b;

MeSH annotation : DF: C3B INACT;

Is substance : O;

Details

Origin ID

D003180;

UMLS CUI

C0009512;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Complement factor I [OMIM gene]
- obsolete complement factor I activity [GO term]
Indexing information
- serine proteinase P-57 [MeSH Supplementary Concept]
Pharmacological action(s)
- complement inactivating agents [MeSH Descriptor]
Record concept(s)
- complement C3b inactivator proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- C3bINA [MeSH Supplementary Concept]
- CFHR1 protein, human [MeSH Supplementary Concept]
- CFHR2 protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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