coformycin - CISMeF

Preferred Label : coformycin;

MeSH definition : A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is proposed as an antineoplastic synergist and immunosuppressant.;

MeSH CAS label : Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-;

Registry Number MeSH : 11033-22-0;

MeSH annotation : an enzyme inhib & antineoplastic antibiotic;

Is substance : O;

Details

Origin ID

D003070;

UMLS CUI

C0009239;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- coformycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3,6,7,8-tetrahydro-3-((2-hydroxyethoxy)methyl)imidazo(4,5-d)(1,3)diazepin-8-ol [MeSH Supplementary Concept]
- carbocyclic coformycin [MeSH Supplementary Concept]
- isocoformycin [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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