choline kinase

Preferred Label : choline kinase;

MeSH definition : An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. EC 2.7.1.32.;

MeSH synonym : kinase, choline; choline phosphokinase; atp choline transphosphatase; choline transphosphatase, atp; phosphokinase, choline; transphosphatase, atp choline;

MeSH CAS label : ATP:choline phosphotransferase;

MeSH Related Number : 9026-67-9 (CAS RN);

Registry Number MeSH : EC 2.7.1.32;

Is substance : O;

UNII : EC 2.7.1.32;

Details

Origin ID

D002797;

UMLS CUI

C0008415;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CHKA wt Allele [NCIt concept]
Currated CISMeF NLP mapping
- Choline kinase (substance) [SNOMED CT concept]
- choline kinase [SNOMED Notion]
Indexing information
- 1,1'-(ethylenebis(benzene-1,4-diylmethylene))bis(7-chloro-4-(pyrrolidino)quinolinium) [MeSH Supplementary Concept]
- N-(3,5-dimethylphenyl)-2-((5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl)sulfanyl)acetamide [MeSH Supplementary Concept]
Record concept(s)
- choline kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CHKA protein, human [MeSH Supplementary Concept]
- CHKB protein, human [MeSH Supplementary Concept]
- Chka protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Choline kinase (substance) [SNOMED CT concept]
- choline kinase [SNOMED Notion]
Validated automatic mappings to BTNT
- Choline Kinase Alpha [NCIt concept]

Keyword's position in hierarchy(ies) :

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