cardiac glycosides

Preferred Label : cardiac glycosides;

MeSH definition : Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA( )-K( )-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.;

MeSH synonym : glycosides, cardiac; steroids, cardiotonic; cardiotonic steroids; Cardiac Glycoside; Glycoside, Cardiac; Cardiotonic Steroid; Steroid, Cardiotonic;

Wikipedia link : https://en.wikipedia.org/wiki/Cardiac glycoside;

Is substance : O;

Details

Origin ID

D002301;

UMLS CUI

C0007158;

ATC code(s)
- other cardiac glycosides [ATC Code]
- scilla glycosides [ATC Code]
ATC code(s)
- cardiac glycosides [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cardiac glycosides [ICD-11 Extension code]
- Digitalin (e) [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Cardiac glycosides [LOINC hierarchical part]
Indexing information
- 17-(3'-thiophenyl)androstane-3,14-diol 3-glucopyranoside [MeSH Supplementary Concept]
- 22,23-dihydrobufalin [MeSH Supplementary Concept]
- 3-(4-azido-3-iodophenyl)propionamide-4-(4,6-dideoxyglucosyl)digitoxigenin [MeSH Supplementary Concept]
- ASI-222 [MeSH Supplementary Concept]
- SC 4453 [MeSH Supplementary Concept]
- acrihellin [MeSH Supplementary Concept]
- adonitoxin [MeSH Supplementary Concept]
- anvirzel [MeSH Supplementary Concept]
- asclepin [MeSH Supplementary Concept]
- bryophyllin A [MeSH Supplementary Concept]
- bryotoxin A [MeSH Supplementary Concept]
- bryotoxin B [MeSH Supplementary Concept]
- cannogenin thevetoside [MeSH Supplementary Concept]
- cannogenol-3-O-alpha-L-rhamnoside [MeSH Supplementary Concept]
- cannogenol-3-O-beta-D-allomethyloside [MeSH Supplementary Concept]
- cardiac glycoside receptors [MeSH Supplementary Concept]
- cerberin [MeSH Supplementary Concept]
- corchoroside A [MeSH Supplementary Concept]
- corchoroside B [MeSH Supplementary Concept]
- cotyledoside [MeSH Supplementary Concept]
- cymarol [MeSH Supplementary Concept]
- digitoxigenin arabinoside [MeSH Supplementary Concept]
- digitoxigenin-galactose [MeSH Supplementary Concept]
- erysimoside [MeSH Supplementary Concept]
- evomonoside [MeSH Supplementary Concept]
- glucoolitoriside [MeSH Supplementary Concept]
- gomphoside [MeSH Supplementary Concept]
- hellebrin [MeSH Supplementary Concept]
- helveticosol 3',4'-dinitrate [MeSH Supplementary Concept]
- methylepoxyproscillaridin [MeSH Supplementary Concept]
- oleandrin [MeSH Supplementary Concept]
- olitoriside [MeSH Supplementary Concept]
- pennogenin tetraglycoside [MeSH Supplementary Concept]
- scillaren A [MeSH Supplementary Concept]
- scillicyanoside [MeSH Supplementary Concept]
- scilliroside [MeSH Supplementary Concept]
- thevetin B [MeSH Supplementary Concept]
- uzarigenin-glucoside-canaroside [MeSH Supplementary Concept]
Metaterm(s)
- cardiology [CISMeF Metaterm]
Pharmacological action(s)
- anti-arrhythmia agents [MeSH Descriptor]
- cardiotonic agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- cardiac glycosides [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2'-O-acetylacoschimperoside P [MeSH Supplementary Concept]
- 2'-epi-2'-O-acetylthevetin B [MeSH Supplementary Concept]
- 24-azido-3-((2,6-dideoxy-beta-hexapyranosyl)oxy)-14-hydroxy-21-norchol-20(22)-en-23-one [MeSH Supplementary Concept]
- 3beta-O-(alpha-L-rhamnopyranosyl)-14beta-hydroperoxy-5beta-hydroxy-19-oxo-17beta-card-20(22)-enolide [MeSH Supplementary Concept]
- 7,8-epoxysinogenin 3-methylglycosides [MeSH Supplementary Concept]
- Cor-Vel liquid [MeSH Supplementary Concept]
- GHSC-73 [MeSH Supplementary Concept]
- TXA9 compound [MeSH Supplementary Concept]
- acetyltanghinin [MeSH Supplementary Concept]
- acetylthevetin B [MeSH Supplementary Concept]
- bovoside [MeSH Supplementary Concept]
- calotropagenin [MeSH Supplementary Concept]
- cardiodigin [MeSH Supplementary Concept]
- codeine, cardiac glycosides drug combination [MeSH Supplementary Concept]
- cryptosin [MeSH Supplementary Concept]
- cuspidoside [MeSH Supplementary Concept]
- deglucohyrcanoside [MeSH Supplementary Concept]
- digitoxigenin 3-O-(O-glucopyranosyl-(1-4)-2-O-acetyldigitalopyranoside) [MeSH Supplementary Concept]
- erysimin G [MeSH Supplementary Concept]
- ghalakinoside [MeSH Supplementary Concept]
- hydroxydihydrobovolide [MeSH Supplementary Concept]
- hyrcanoside [MeSH Supplementary Concept]
- maquiroside A [MeSH Supplementary Concept]
- miroton [MeSH Supplementary Concept]
- oleandrigenin-3-O-alpha-2'-O-acetylvallaropyranoside [MeSH Supplementary Concept]
- oleandrigenin-beta-D-glucosyl (1-4)-beta-D-digitalose [MeSH Supplementary Concept]
- periplocymarin [MeSH Supplementary Concept]
- periplogenin 3-O-(O-glucopyranosyl-(1-4)-O-glucopyranosyl-(1-4)-cymaropyranoside) [MeSH Supplementary Concept]
- proceraside A [MeSH Supplementary Concept]
- rohdealine [MeSH Supplementary Concept]
- scillaren [MeSH Supplementary Concept]
- strebloside- [MeSH Supplementary Concept]
- strospeside [MeSH Supplementary Concept]
- tanghinin [MeSH Supplementary Concept]
- thevetoside [MeSH Supplementary Concept]
- toxicarioside A [MeSH Supplementary Concept]
- toxicarioside F [MeSH Supplementary Concept]
- toxicarioside G [MeSH Supplementary Concept]
- toxicarioside H [MeSH Supplementary Concept]
- venocuran [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Cardiac glycosides [LOINC hierarchical part]
- Glycoside [NCIt concept]
- Glycoside (substance) [SNOMED CT concept]
- Product containing glycoside (product) [SNOMED CT concept]
- cardiac glycosides [ATC Code]
- glycoside, nos [SNOMED Notion]
Validated automatic mappings to BTNT
- cardiac glycosides [ATC Code]
- other cardiac glycosides [ATC Code]
Validated automatic mappings to NTBT
- Glycoside [NCIt concept]
- Glycoside (substance) [SNOMED CT concept]
- Product containing glycoside (product) [SNOMED CT concept]
- glycoside, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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