MeSH definition : Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the
liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous
plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion
of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and
valve regurgitation.;
Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the
liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous
plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion
of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and
valve regurgitation.