cantharidin - CISMeF

Preferred Label : cantharidin;

MeSH definition : A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.;

MeSH synonym : Cantharidine;

CISMeF synonym : (1r,2s,3r,6s)-1,2-dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride;

Related MeSH term : cantharides;

MeSH CAS label : 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-;

MeSH Related Number : 56-25-7 (Cantharidin);

Registry Number MeSH : 56-25-7;

Wikipedia link : https://en.wikipedia.org/wiki/Cantharidin;

Codes EINECS : 200-263-3;

Is substance : O;

UNII : IGL471WQ8P;

InChIKey : DHZBEENLJMYSHQ-XCVPVQRUSA-N;

Details

Origin ID

D002193;

UMLS CUI

C0006886;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cantharides [ICD-11 Extension code]
- Product containing cantharidin (medicinal product) [SNOMED CT concept]
- lytta vesicatoria [SNOMED Notion]
CISMeF manual mappings
- (1r,2s,3r,6s)-1,2-dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride [Substance BNPC]
Currated CISMeF NLP mapping
- Cantharidin [NCIt concept]
- Cantharidin (substance) [SNOMED CT concept]
- cantharidin [SNOMED Notion]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
- irritants [MeSH Descriptor]
- riot control agents, chemical [MeSH Descriptor]
Record concept(s)
- cantharides [MeSH concept]
- cantharidin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-tetradecylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione [MeSH Supplementary Concept]
- CAN 032 [MeSH Supplementary Concept]
- N-benzylcantharidinamide [MeSH Supplementary Concept]
- N-farnesyl-norcantharimide [MeSH Supplementary Concept]
- N-farnesyloxy-norcantharimide [MeSH Supplementary Concept]
- N-hydroxycantharidinimide [MeSH Supplementary Concept]
- VP-102 [MeSH Supplementary Concept]
- cantharidic acid [MeSH Supplementary Concept]
- cantharidin methylimide [MeSH Supplementary Concept]
- demethylcantharidin [MeSH Supplementary Concept]
- disodium cantharidin [MeSH Supplementary Concept]
- hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione [MeSH Supplementary Concept]
- sodium cantharidate [MeSH Supplementary Concept]
See also
- Cantharis vesicatoria [DeCS]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- (1r,2s,3r,6s)-1,2-dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride [Substance BNPC]
- Cantharidin [NCIt concept]
- Cantharidin (substance) [SNOMED CT concept]
- Product containing cantharidin (medicinal product) [SNOMED CT concept]
- cantharidin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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