bromouracil - CISMeF

Preferred Label : bromouracil;

MeSH definition : 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.;

MeSH synonym : 5-bromouracil; bromuracil; 5 bromouracil;

MeSH CAS label : 2,4(1H,3H)-Pyrimidinedione, 5-bromo-;

MeSH Related Number : 51-20-7 (Bromouracil);

Registry Number MeSH : 51-20-7;

MeSH annotation : an antimetabolite;

Codes EINECS : 200-084-0;

Is substance : O;

UNII : 4HK400G5UO;

InChIKey : LQLQRFGHAALLLE-UHFFFAOYSA-N;

Details

Origin ID

D001976;

UMLS CUI

C0006242;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 5-bromouracil [Substance BNPC]
Pharmacological action(s)
- antimetabolites [MeSH Descriptor]
- mutagens [MeSH Descriptor]
Record concept(s)
- bromouracil [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,1'(2''-bromo-2''-chloroethenyl)-bis-(5-bromouracil) [MeSH Supplementary Concept]
- 1-(2-fluoro-2-deoxy-3,5-O-dibenzoylarabinofuranosyl)-5-bromouracil [MeSH Supplementary Concept]
- 1-(2-fluoro-2-deoxyarabinofuranosyl)-5-bromouracil [MeSH Supplementary Concept]
- 1-amino-5-bromouracil [MeSH Supplementary Concept]
- 1-methyl-5-bromouracil [MeSH Supplementary Concept]
- 5-(2-bromovinyl)uracil [MeSH Supplementary Concept]
- 5-bromo-1,3,6-trimethyluracil [MeSH Supplementary Concept]
- 5-bromo-6-azauracil [MeSH Supplementary Concept]
- 5-bromouridine [MeSH Supplementary Concept]
- 6-amino-5-bromouracil [MeSH Supplementary Concept]
- bromacil [MeSH Supplementary Concept]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- 5-bromouracil [Substance BNPC]

Keyword's position in hierarchy(ies) :

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