bicuculline - CISMeF

Preferred Label : bicuculline;

MeSH definition : An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.;

MeSH synonym : 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one;

MeSH CAS label : Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-;

MeSH Related Number : 485-49-4 (Bicuculline);

Registry Number MeSH : 485-49-4;

Wikipedia link : https://en.wikipedia.org/wiki/Bicuculline;

Codes EINECS : 207-619-7;

Is substance : O;

UNII : Y37615DVKC;

Details

Origin ID

D001640;

UMLS CUI

C0005372;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Bicucculine [ICHI extension code]
CISMeF manual mappings
- bicuculline [Substance BNPC]
Currated CISMeF NLP mapping
- Bicucculine [ICD-11 Extension code]
Pharmacological action(s)
- GABA-A receptor antagonists [MeSH Descriptor]
- convulsants [MeSH Descriptor]
Record concept(s)
- bicuculline [MeSH concept]
Related MeSH Supplementary Concept(s)
- bicuculline methiodide [MeSH Supplementary Concept]
- bicuculline methobromide [MeSH Supplementary Concept]
- bicuculline methochloride [MeSH Supplementary Concept]
- bicuculline methoxide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bicucculine [ICD-11 Extension code]
- bicuculline [Substance BNPC]

Keyword's position in hierarchy(ies) :

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