" /> beta-n-acetylhexosaminidases - CISMeF





Preferred Label : beta-n-acetylhexosaminidases;

MeSH definition : A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.;

MeSH synonym : beta n acetylhexosaminidase; beta-n-acetyl-hexosaminidase; beta-n-acetyl-d-hexosaminidase; beta hexosaminidase; beta n acetyl d hexosaminidase; n-acetyl-beta-d-hexosaminidase; n acetyl beta d hexosaminidase; beta n acetyl hexosaminidase; beta-n-acetylhexosaminidase; beta-hexosaminidase; beta N acetylhexosaminidases;

MeSH CAS label : beta-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase;

Registry Number MeSH : EC 3.2.1.52;

MeSH annotation : do not confuse with ACETYLGLUCOSAMINIDASE; /defic: consider also TAY SACHS DISEASE and SANDHOFF DISEASE;

Is substance : O;

UNII : EC 3.2.1.52;

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A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.

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14/05/2024


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