MeSH definition : An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP
to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate
or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent
factor, is located in the relA gene in stringent strains of bacteria. The above synthesis
is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding
site of the ribosome by a codon-specific association. EC 2.7.6.5.;
An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP
to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate
or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent
factor, is located in the relA gene in stringent strains of bacteria. The above synthesis
is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding
site of the ribosome by a codon-specific association. EC 2.7.6.5.