argininosuccinate synthase

Preferred Label : argininosuccinate synthase;

MeSH definition : An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.;

MeSH synonym : argininosuccinate synthetase; synthetase, argininosuccinate; synthase, argininosuccinate;

MeSH CAS label : L-Citrulline:L-aspartate ligase (AMP-forming);

MeSH Related Number : 9023-58-9 (CAS RN);

Registry Number MeSH : EC 6.3.4.5;

MeSH annotation : /defic: consider also CITRULLINEMIA;

Wikipedia link : https://en.wikipedia.org/wiki/Argininosuccinate synthase;

Is substance : O;

UNII : EC 6.3.4.5;

Details

Origin ID

D001124;

UMLS CUI

C0003776;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- argininosuccinate synthase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ArgG protein, E coli [MeSH Supplementary Concept]
- arginine synthetase system [MeSH Supplementary Concept]
See also
- citrullinemia [MeSH Descriptor]
See also inter- (CISMeF)
- argininosuccinate synthase activity [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Argininosuccinate synthase [LOINC component]
- Argininosuccinate synthetase (substance) [SNOMED CT concept]
- argininosuccinate synthase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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