Preferred Label : antigens, polyomavirus transforming;
MeSH definition : Polyomavirus antigens which cause infection and cellular transformation. The large
T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription
of the early region and is responsible in conjunction with the middle T antigen for
the transformation of primary cells. Small T antigen is necessary for the completion
of the productive infection cycle.;
MeSH synonym : antigens, polyomavirus tumor; polyomavirus transforming antigens; polyomavirus tumor antigens; transforming antigens, polyomavirus; tumor antigens, polyomavirus;
MeSH hyponym : simian sarcoma virus proteins; polyomavirus small T antigens; polyomavirus large T antigens; polyomavirus middle T antigens; polyomavirus T proteins; SV40 T proteins; Proteins, Polyomavirus T; T Proteins, Polyomavirus; Polyomaviruses Middle T Proteins; Polyomaviruses Small T Proteins; Proteins, SV40 T; T Proteins, SV40; SV40 T Antigens; Antigens, SV40 T; T Antigens, SV40; Polyomaviruses Large T Proteins;
MeSH annotation : coord IM with specific polyoma virus /immunol (IM); DF: PVTA; coordinate with specific polyoma virus /immunol;
Is substance : O;
Origin ID : D000952;
UMLS CUI : C0003337;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
Polyomavirus antigens which cause infection and cellular transformation. The large
T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription
of the early region and is responsible in conjunction with the middle T antigen for
the transformation of primary cells. Small T antigen is necessary for the completion
of the productive infection cycle.
