Sodium-Potassium-Exchanging ATPase

Preferred Label : Sodium-Potassium-Exchanging ATPase;

MeSH definition : An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.;

MeSH synonym : sodium pump; sodium, potassium atpase; atpase sodium, potassium; pump, potassium; sodium potassium pump; na( ) k( )-transporting atpase; na( )-k( )-transporting atpase; adenosinetriphosphatase sodium, potassium; sodium, potassium adenosinetriphosphatase; adenosinetriphosphatase, sodium, potassium; adenosine triphosphatase, sodium, potassium; atpase, sodium-potassium-exchanging; sodium-potassium pump; na( )-k( )-exchanging atpase; pump, sodium; potassium pump; sodium, potassium adenosine triphosphatase; pump, sodium-potassium; atpase, sodium, potassium; sodium potassium exchanging ATPase;

MeSH CAS label : ATP phosphohydrolase (Na( )-K( )-transporting);

Registry Number MeSH : EC 3.6.3.9;

MeSH annotation : DF: NA K ATPASE;

Wikipedia link : https://en.wikipedia.org/wiki/Sodium-potassium pump;

Is substance : O;

UNII : EC 7.2.2.13;

Details

Origin ID

D000254;

UMLS CUI

C0001479;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ATPase H+/K+ transporting non-gastric alpha2 subunit [HGNC gene]
- Na^+^/K^+^-transporting adenosine triphosphatase (substance) [SNOMED CT concept]
- na+/k+-transporting atpase [SNOMED Notion]
- sodium:potassium-exchanging ATPase activity [GO term]
- sodium:potassium-exchanging ATPase complex [GO term]
False automatic mappings
- h+-transporting atpase [SNOMED Notion]
Indexing information
- 1,3-dibromo-2,4,6-tris-(methylisothiouronium)benzene [MeSH Supplementary Concept]
- 11,13-dihydroxy-14-octadecaenoic acid [MeSH Supplementary Concept]
- 17-(((4-aminobutoxy)imino)methyl)-5-androstane-3,14-diol [MeSH Supplementary Concept]
- 17-(2-((2-aminoethoxy)imino)ethyl)androstane-3,14-diol [MeSH Supplementary Concept]
- 17-(3-((2-dimethylaminoethoxy)imino)propyl)-5-androstane-3,14-diol [MeSH Supplementary Concept]
- 2-((2,4-dimethoxybenzyl)sulfinyl)-N-(4-pyridyl)nicotinamide [MeSH Supplementary Concept]
- 2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole [MeSH Supplementary Concept]
- 3-hydroxy-17-(2-((2-(N,N-dimethylamino)ethoxy)imino)ethyl)-14,15-secoandrostan-14-one [MeSH Supplementary Concept]
- 4,7-diacetoxy-14-hydroxydolast-1(15),8-diene [MeSH Supplementary Concept]
- 4-(diazomethyl)-7-(diethylamino)coumarin [MeSH Supplementary Concept]
- 4-acetoxy-9,14-dihydroxydolast-1(15),7-diene [MeSH Supplementary Concept]
- 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride [MeSH Supplementary Concept]
- 6'-O-(4-hydroxycinnamoyl)desglucouzarin [MeSH Supplementary Concept]
- 6'-hydroxy-16alpha-acetoxycalactin [MeSH Supplementary Concept]
- 6'-hydroxycalactin [MeSH Supplementary Concept]
- 6-(decyldithio)-1H-purin-2-amine [MeSH Supplementary Concept]
- 6-(decyldithio)-1H-purine [MeSH Supplementary Concept]
- 6-(phenyldithio)-1H-purin-2-amine [MeSH Supplementary Concept]
- 6-(phenyldithio)purine [MeSH Supplementary Concept]
- 6-tridecylresorcylic acid [MeSH Supplementary Concept]
- 8-methoxy-3,9-dihydroxycoumestan [MeSH Supplementary Concept]
- B 8301-078 [MeSH Supplementary Concept]
- FK 409 [MeSH Supplementary Concept]
- L 681110 [MeSH Supplementary Concept]
- LND 623 [MeSH Supplementary Concept]
- NC 1300 B [MeSH Supplementary Concept]
- PD 118576-A1 [MeSH Supplementary Concept]
- PD 118576-A2 [MeSH Supplementary Concept]
- PD 118576-A3 [MeSH Supplementary Concept]
- SPAI-1 protein, sus scrofa [MeSH Supplementary Concept]
- SPAI-2 protein, sus scrofa [MeSH Supplementary Concept]
- SPAI-3 protein, sus scrofa [MeSH Supplementary Concept]
- acetyltylophoroside [MeSH Supplementary Concept]
- adenosine-5-N'-(2,4-dinitro-5-fluorophenyl)phosphohydrazine [MeSH Supplementary Concept]
- agelasidine C [MeSH Supplementary Concept]
- agelasine B [MeSH Supplementary Concept]
- alloxantin [MeSH Supplementary Concept]
- aplysiallene [MeSH Supplementary Concept]
- atrial natriuretic factor precursor (79-98) [MeSH Supplementary Concept]
- bufalin [MeSH Supplementary Concept]
- cardiodigin [MeSH Supplementary Concept]
- chlormadinol acetate [MeSH Supplementary Concept]
- chloroprotohemin IX [MeSH Supplementary Concept]
- chromium-adenosine 5'-(beta,gamma-methylene)triphosphate complex [MeSH Supplementary Concept]
- cobalt tetraammine phosphate [MeSH Supplementary Concept]
- digoxin-like factors [MeSH Supplementary Concept]
- emicymarin [MeSH Supplementary Concept]
- endobain E [MeSH Supplementary Concept]
- epoxyscillirosidin [MeSH Supplementary Concept]
- grevillol [MeSH Supplementary Concept]
- halenaquinol [MeSH Supplementary Concept]
- iantheran A [MeSH Supplementary Concept]
- iantheran B [MeSH Supplementary Concept]
- istaroxime [MeSH Supplementary Concept]
- linsidomine [MeSH Supplementary Concept]
- marinosin [MeSH Supplementary Concept]
- methyl 2-(3,4-dimethoxystyryl)benzimidazole-4-carboxylate [MeSH Supplementary Concept]
- pentagalloylglucose [MeSH Supplementary Concept]
- ptilomycalin A [MeSH Supplementary Concept]
- ro 18-5364 [MeSH Supplementary Concept]
- shihunidine [MeSH Supplementary Concept]
- shihunine [MeSH Supplementary Concept]
- sodium-potassium ATPase inhibitory factor [MeSH Supplementary Concept]
- sodium-translocating ATPase [MeSH Supplementary Concept]
- tylogenin [MeSH Supplementary Concept]
Record concept(s)
- Sodium-Potassium-Exchanging ATPase [MeSH concept]
Related MeSH Supplementary Concept(s)
- 3-O-methyl-fluorescein phosphatase [MeSH Supplementary Concept]
- ATP1A1 protein, C elegans [MeSH Supplementary Concept]
- ATP1A1 protein, human [MeSH Supplementary Concept]
- ATP1A2 protein, Xenopus [MeSH Supplementary Concept]
- ATP1A2 protein, human [MeSH Supplementary Concept]
- ATP1A3 protein, Xenopus [MeSH Supplementary Concept]
- ATP1A3 protein, human [MeSH Supplementary Concept]
- ATP1A3 protein, zebrafish [MeSH Supplementary Concept]
- ATP1A4 protein, human [MeSH Supplementary Concept]
- ATP1B1 protein, human [MeSH Supplementary Concept]
- ATP1B3 protein, human [MeSH Supplementary Concept]
- ATP1B4 protein, human [MeSH Supplementary Concept]
- ATPalpha protein, drosophila [MeSH Supplementary Concept]
- Atp1a1 protein, mouse [MeSH Supplementary Concept]
- Atp1a1 protein, rat [MeSH Supplementary Concept]
- Atp1a2 protein, mouse [MeSH Supplementary Concept]
- Atp1a2 protein, rat [MeSH Supplementary Concept]
- Atp1a3 protein, mouse [MeSH Supplementary Concept]
- Atp1a3 protein, rat [MeSH Supplementary Concept]
- Atp1a4 protein, mouse [MeSH Supplementary Concept]
- Atp1a4 protein, rat [MeSH Supplementary Concept]
- Atp1b1 protein, mouse [MeSH Supplementary Concept]
- Atp1b1 protein, rat [MeSH Supplementary Concept]
- Atp1b3 protein, mouse [MeSH Supplementary Concept]
- Atp1b4 protein, mouse [MeSH Supplementary Concept]
- ENA1 protein, S cerevisiae [MeSH Supplementary Concept]
- FXYD2 protein, human [MeSH Supplementary Concept]
- Fxyd2 protein, mouse [MeSH Supplementary Concept]
- Fxyd2 protein, rat [MeSH Supplementary Concept]
- NaKtide [MeSH Supplementary Concept]
- Nrv3 protein, drosophila [MeSH Supplementary Concept]
- PpENA1 protein, physcomitrella patens [MeSH Supplementary Concept]
- YcfA protein, erwinia amylovora [MeSH Supplementary Concept]
- alpha2 protein, Na(+)-K(+)-exchanging ATPase, zebrafish [MeSH Supplementary Concept]
- atp1a1 protein, xenopus [MeSH Supplementary Concept]
- atp1a1a.1 protein, zebrafish [MeSH Supplementary Concept]
- atp1a1b protein, zebrafish [MeSH Supplementary Concept]
- cardiac glycoside receptors [MeSH Supplementary Concept]
- digitalis receptor [MeSH Supplementary Concept]
- magnesium sodium potassium ATPase [MeSH Supplementary Concept]
- na K ATPase beta2 subunit, rat [MeSH Supplementary Concept]
- slc8a4a protein, zebrafish [MeSH Supplementary Concept]
- sodium potassium ATPase alpha3 subunit, human [MeSH Supplementary Concept]
See also
- potassium channels [MeSH Descriptor]
- sodium channels [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Na^+^/K^+^-transporting adenosine triphosphatase (substance) [SNOMED CT concept]
- na+/k+-transporting atpase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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