Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

Preferred Label : Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase;

MeSH definition : A nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP in mammals. This activates the STING1 PROTEIN through the CGAS-STING SIGNALING PATHWAY, which triggers the production of INTERFERON TYPE I and other CYTOKINES.;

MeSH synonym : cGAS Protein; Cyclic GMP-AMP Synthase;

UNII : EC 2.7.7.86;

Details

Origin ID

D000099235;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase [MeSH concept]
Related MeSH Supplementary Concept(s)
- Cgas protein, rat [MeSH Supplementary Concept]
- cGAS protein, human [MeSH Supplementary Concept]
- cGAS protein, mouse [MeSH Supplementary Concept]

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