cGAS-STING Signaling Pathway

Preferred Label : cGAS-STING Signaling Pathway;

MeSH definition : A signal transduction pathway that involves cGMP-AMP synthase (cGAS), stimulator of interferon genes (STING), and downstream signaling adaptors. This pathway plays an essential role in the innate immune system by activating immune defenses, particularly against invading pathogens or harmful damage.;

MeSH synonym : (cGAS-STING) Pathway; cGAS-STING cascade; cGAS-STING Signaling; cGAS–STING Cytosolic DNA Sensing Pathway;

MeSH hyponym : cGAS-STING Innate Immunity Pathway;

Details

Origin ID

D000099196;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Indexing information
- STING1 protein, human [MeSH Supplementary Concept]
- Sting1 protein, mouse [MeSH Supplementary Concept]
- Sting1 protein, rat [MeSH Supplementary Concept]
Record concept(s)
- cGAS-STING Activation [MeSH concept]
- cGAS-STING Immunity Pathway [MeSH concept]
- cGAS-STING Signaling Pathway [MeSH concept]

Keyword's position in hierarchy(ies) :

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