Preferred Label : Natural Resistance-associated Macrophage Protein 1;
MeSH definition : A cation transport protein that shares structural homology with prokaryotic and eukaryotic
transport proteins. In mammals, it is a MACROPHAGE-specific antiporter, transporting
metal ions in either direction against a proton gradient, and localizes to membranes
of late ENDOSOMES and LYSOSOMES, where it may contribute to antimicrobial activity.;
MeSH synonym : Natural Resistance-associated Macrophage Protein; Nramp Protein; Nramp1 Protein; SLC11A1 Protein; Solute Carrier 11a1; Solute Carrier Family 11-(proton-coupled divalent metal ion transporters), Member
1;
Origin ID : D000099173;
Allowable qualifiers
- Record concept(s)
- Related MeSH Supplementary Concept(s)
A cation transport protein that shares structural homology with prokaryotic and eukaryotic
transport proteins. In mammals, it is a MACROPHAGE-specific antiporter, transporting
metal ions in either direction against a proton gradient, and localizes to membranes
of late ENDOSOMES and LYSOSOMES, where it may contribute to antimicrobial activity.
