Mitochondrial Processing Peptidase

Preferred Label : Mitochondrial Processing Peptidase;

MeSH definition : A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.;

Définition CISMeF : https://en.wikipedia.org/wiki/Mitochondrial_processing_peptidase;

MeSH synonym : Peptidase, Mitochondrial Processing; Processing Peptidase, Mitochondrial; Mitochondrial Processing Protease; Processing Protease, Mitochondrial; Protease, Mitochondrial Processing; Matrix Processing Peptidase; Peptidase, Matrix Processing; Processing Peptidase, Matrix;

MeSH hyponym : beta MPP; alpha MPP;

UNII : EC 3.4.24.64;

Details

Origin ID

D000096122;

UMLS CUI

C0128584;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Mitochondrial processing peptidase (substance) [SNOMED CT concept]
Record concept(s)
- alpha-MPP [MeSH concept]
- beta-MPP [MeSH concept]
- mitochondrial processing peptidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- MPPA protein, rat [MeSH Supplementary Concept]
- MPPB protein, rat [MeSH Supplementary Concept]
- Mas1 protein, S cerevisiae [MeSH Supplementary Concept]
- PMPCA protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Mitochondrial processing peptidase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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