Preferred Label : Propionyl-Coenzyme A Carboxylase;
MeSH definition : Mitochondrial carboxylase that is involved in the catabolism of odd chain fatty acids
and branched amino acids. Dysfunction of propionyl-CoA carboxylase leads to the inherited
metabolic disorder PROPIONIC ACIDEMIA. In bacteria it is an ATP-dependent carboxylase
in CO2 fixation reactions where propionyl-CoA is converted to (S)-methylmalonyl-CoA.;
MeSH synonym : Carboxylase, Propionyl-Coenzyme A; Propionyl Coenzyme A Carboxylase; Propionyl-CoA Carboxylase; Propionyl CoA Carboxylase;
Mitochondrial carboxylase that is involved in the catabolism of odd chain fatty acids
and branched amino acids. Dysfunction of propionyl-CoA carboxylase leads to the inherited
metabolic disorder PROPIONIC ACIDEMIA. In bacteria it is an ATP-dependent carboxylase
in CO2 fixation reactions where propionyl-CoA is converted to (S)-methylmalonyl-CoA.