MeSH definition : A subset of activated B cells generated in response to primary immune challenge or
immunization which are capable of giving rise to antibody-secreting cells upon re-challenge
(see IMMUNOLOGIC MEMORY). Memory B cells feature many discrete properties indicative
of differentiation through ISOTYPE SWITCHING and/or IMMUNOGLOBULIN SOMATIC HYPERMUTATION
for rapid and robust recall of specific antibody responses.;
MeSH synonym : B Cell, Memory; Memory B Cell; Memory B-Lymphocytes; B-Lymphocyte, Memory; B-Lymphocytes, Memory; Memory B Lymphocytes; Memory B-Lymphocyte;
A subset of activated B cells generated in response to primary immune challenge or
immunization which are capable of giving rise to antibody-secreting cells upon re-challenge
(see IMMUNOLOGIC MEMORY). Memory B cells feature many discrete properties indicative
of differentiation through ISOTYPE SWITCHING and/or IMMUNOGLOBULIN SOMATIC HYPERMUTATION
for rapid and robust recall of specific antibody responses.