Immune Checkpoint Proteins

Preferred Label : Immune Checkpoint Proteins;

MeSH definition : Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.;

MeSH synonym : Immune Checkpoint Molecules; Immune Checkpoint Protein; Checkpoint Protein, Immune; Protein, Immune Checkpoint; Immune Checkpoint Molecule; Checkpoint Molecule, Immune; Molecule, Immune Checkpoint;

MeSH hyponym : Stimulatory Checkpoint Molecule; Checkpoint Molecule, Stimulatory; Inhibitory Checkpoint Molecule; Checkpoint Molecule, Inhibitory;

Details

Origin ID

D000082102;

UMLS CUI

C5392070;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Immune Checkpoint Proteins [MeSH concept]
- Inhibitory Checkpoint Molecules [MeSH concept]
- Stimulatory Checkpoint Molecules [MeSH concept]
Related MeSH term(s)
- Immune Checkpoint Inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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