Protein-Arginine Deiminase Type 4

Preferred Label : Protein-Arginine Deiminase Type 4;

MeSH definition : A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.;

MeSH synonym : PADI4 Protein; Peptidylarginine Deiminase V; PAD V Enzyme; PADI5 Protein; Protein Arginine Deiminase 4; Protein Arginine Deiminase Type 4; Protein Arginine Deiminase Type IV; Protein-Arginine Deiminase Type IV; Peptidylarginine Deiminase IV; Peptidylarginine Deiminase Type IV; Peptidylarginine Deiminase Type 4; Peptidyl Arginine Deiminase Type IV; Peptidyl Arginine Deiminase Type 4;

UNII : EC 3.5.3.15;

Details

Origin ID

D000080002;

UMLS CUI

C0765808;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Protein-Arginine Deiminase Type 4 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PADI4 protein, human [MeSH Supplementary Concept]
- peptidylarginine deiminase 4, mouse [MeSH Supplementary Concept]
- peptidylarginine deiminase 4, rat [MeSH Supplementary Concept]
See also
- Citrullination [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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