O-(Chloroacetylcarbamoyl)fumagillol

Preferred Label : O-(Chloroacetylcarbamoyl)fumagillol;

MeSH definition : Semisynthetic analog of fumagillin (a cyclohexane-sesquiterpene antibiotic isolated from ASPERGILLUS FUMIGATUS) that inhibits angiogenesis.;

MeSH synonym : 5-Methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2,5)oct-6-yl(chloroacetyl) carbamate;

MeSH hyponym : AGM-1470; AGM1470; TNP-470; TNP470;

MeSH Related Number : 129298-91-5 (O-(chloroacetylcarbamoyl)fumagillol);

UNII : X47GR46481;

Details

Origin ID

D000077609;

UMLS CUI

C0081489;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- O-Chloroacetylcarbamoylfumagillol [NCIt concept]
Pharmacological action(s)
- angiogenesis inhibitors [MeSH Descriptor]
- antibiotics, antineoplastic [MeSH Descriptor]
Record concept(s)
- AGM 1470 [MeSH concept]
- O-(chloroacetylcarbamoyl)fumagillol [MeSH concept]
- TNP 470 [MeSH concept]
- caplostatin [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- O-Chloroacetylcarbamoylfumagillol [NCIt concept]

Keyword's position in hierarchy(ies) :

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