MeSH definition : Clinical study in which a prospectively planned opportunity is included to modify
trial designs and hypotheses based on analysis of data from subjects in the study.;
MeSH annotation : this heading is used as a Publication Type; for original report of the conduct or
results of a specific adaptive clinical trial; a different heading ADAPTIVE CLINICAL
TRIALS AS TOPIC is used for general design, methodology, economics, etc. of adaptive
clinical trials;
Clinical study in which a prospectively planned opportunity is included to modify
trial designs and hypotheses based on analysis of data from subjects in the study.