MeSH definition : Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3'
pentamer DNA sequences and are regulated by poly(ADP) ribosylation. They play essential
roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression
of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function
in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing
and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.; Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3'
pentamer DNA sequences and are regulated by POLY-ADP-RIBOSYLATION. They play essential
roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression
of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function
in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing
and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.;
Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3'
pentamer DNA sequences and are regulated by poly(ADP) ribosylation. They play essential
roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression
of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function
in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing
and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress. Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3'
pentamer DNA sequences and are regulated by POLY-ADP-RIBOSYLATION. They play essential
roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression
of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function
in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing
and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.
Allowable qualifiers