MeSH definition : An Sp transcription factor that contains three CYS2-HIS2 ZINC FINGERS. It binds to
GC RICH SEQUENCES and performs an essential function in regulating gene expression
for differentiation of OSTEOBLASTS. Mutations in the SP7 gene are associated with
type 12 OSTEOGENESIS IMPERFECTA.;
An Sp transcription factor that contains three CYS2-HIS2 ZINC FINGERS. It binds to
GC RICH SEQUENCES and performs an essential function in regulating gene expression
for differentiation of OSTEOBLASTS. Mutations in the SP7 gene are associated with
type 12 OSTEOGENESIS IMPERFECTA.