Ubiquitin-Specific Peptidase 7

Preferred Label : Ubiquitin-Specific Peptidase 7;

MeSH definition : A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.;

MeSH synonym : Peptidase 7, Ubiquitin-Specific; Ubiquitin Specific Peptidase 7; HAUSP Protein; Herpesvirus-Associated Ubiquitin-Specific Peptidase; Herpesvirus Associated Ubiquitin Specific Peptidase; Peptidase, Herpesvirus-Associated Ubiquitin-Specific; Ubiquitin-Specific Peptidase, Herpesvirus-Associated; USP7 Protein;

Registry Number MeSH : EC 3.4.19.12;

UNII : EC 3.4.19.12;

Details

Origin ID

D000076084;

UMLS CUI

C4319698;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ubiquitin specific peptidase 7 [ORDO Gene]
- ubiquitin specific peptidase 7 [HGNC gene]
Record concept(s)
- Ubiquitin-Specific Peptidase 7 [MeSH concept]
Related MeSH Supplementary Concept(s)
- USP7 protein, human [MeSH Supplementary Concept]
- Usp7 protein, mouse [MeSH Supplementary Concept]
- Usp7 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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