Hyaluronan Synthases

Preferred Label : Hyaluronan Synthases;

MeSH definition : Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.;

MeSH synonym : Synthases, Hyaluronan; Hyaluronan Synthase; Synthase, Hyaluronan; Hyaluronic Acid Synthetase; Synthetase, Hyaluronic Acid; Hyaluronate Synthetase; Synthetase, Hyaluronate; Hyaluronan Synthetase; Synthetase, Hyaluronan; Hyaluronate Synthase; Synthase, Hyaluronate;

DeCS synonym : hasA Enzyme; Hyaluronan Synthase 1; Hyaluronan Synthase 2; Hyaluronan Synthase 3;

MeSH hyponym : 3, Hyaluronan Synthase; Synthase 3, Hyaluronan; HAS3 Protein; Protein, HAS3; Synthase 1, Hyaluronan; HAS1 Protein; Synthase 2, Hyaluronan; HAS2 Protein;

Registry Number MeSH : EC 2.4.1.212;

UNII : EC 2.4.1.212;

Details

Origin ID

D000076002;

UMLS CUI

C4318636;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Hyaluronan Synthase 2 [NCIt concept]
- Hyaluronan synthase 1 [OMIM gene]
- Hyaluronan synthase 2 [OMIM gene]
- Hyaluronan synthase 3 [OMIM gene]
- hyaluronan synthase 1 [HGNC gene]
- hyaluronan synthase 2 [HGNC gene]
- hyaluronan synthase 3 [HGNC gene]
Record concept(s)
- Hyaluronan Synthase 1 [MeSH concept]
- Hyaluronan Synthase 2 [MeSH concept]
- Hyaluronan Synthase 3 [MeSH concept]
- Hyaluronan Synthases [MeSH concept]
- hasA Enzyme [MeSH concept]
Related MeSH Supplementary Concept(s)
- HAS1 protein, human [MeSH Supplementary Concept]
- HAS2 protein, human [MeSH Supplementary Concept]
- HAS3 protein, human [MeSH Supplementary Concept]
- HAS3 protein, xenopus [MeSH Supplementary Concept]
- Has1 protein, mouse [MeSH Supplementary Concept]
- Has2 protein, mouse [MeSH Supplementary Concept]
- Has2 protein, rat [MeSH Supplementary Concept]
- Has2 protein, xenopus [MeSH Supplementary Concept]
- Has3 protein, mouse [MeSH Supplementary Concept]
- Has3 protein, rat [MeSH Supplementary Concept]
- has2 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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