Cell Adhesion Molecule-1

Preferred Label : Cell Adhesion Molecule-1;

MeSH definition : A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.;

MeSH synonym : Adhesion Molecule-1, Cell; Cell Adhesion Molecule 1; Molecule-1, Cell Adhesion; CADM1 Protein; Tumor Suppressor in Lung Cancer 1 Protein; IGSF4 Protein; TSLC1 Protein;

Details

Origin ID

D000075982;

UMLS CUI

C4319841;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cell Adhesion Molecule 1 [NCIt concept]
- Cell adhesion molecule 1 [OMIM gene]
- cell adhesion molecule 1 [HGNC gene]
Record concept(s)
- Cell Adhesion Molecule-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CADM1 protein, human [MeSH Supplementary Concept]
- Cadm1 protein, mouse [MeSH Supplementary Concept]
See also
- Immunoglobulin Domains [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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