Elongin - CISMeF

Preferred Label : Elongin;

MeSH definition : A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.;

MeSH synonym : SIII Elongation Factor; Elongation Factor, SIII; TF-SIII; Transcription Factor SIII; SIII, Transcription Factor; Elongin Complex; Complex, Elongin;

DeCS synonym : Elongin C; Elongin B;

MeSH hyponym : EloC Protein; EloA Protein; EloB Protein;

Details

Origin ID

D000075065;

UMLS CUI

C0381110;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Elongin [NCIt concept]
- Elongin a [OMIM gene]
- elongin A [HGNC gene]
- elongin complex [GO term]
Record concept(s)
- Elongin [MeSH concept]
- elongin A [MeSH concept]
- elongin B [MeSH concept]
- elongin C [MeSH concept]
Related MeSH Supplementary Concept(s)
- EBAX-1 protein, C elegans [MeSH Supplementary Concept]
- ELA1 protein, S cerevisiae [MeSH Supplementary Concept]
- ELC1 protein, S cerevisiae [MeSH Supplementary Concept]
- ELOA protein, human [MeSH Supplementary Concept]
- ELOA2 protein, human [MeSH Supplementary Concept]
- ELOA3P pseudogene, human [MeSH Supplementary Concept]
- ELOB protein, human [MeSH Supplementary Concept]
- ELOC protein, human [MeSH Supplementary Concept]
- Eloa protein, mouse [MeSH Supplementary Concept]
- Eloa protein, rat [MeSH Supplementary Concept]
- Elob protein, mouse [MeSH Supplementary Concept]
- Elob protein, rat [MeSH Supplementary Concept]
- Eloc protein, mouse [MeSH Supplementary Concept]
- Eloc protein, rat [MeSH Supplementary Concept]
- elb-1 protein, C elegans [MeSH Supplementary Concept]
- elc-1 protein, C elegans [MeSH Supplementary Concept]
- tceb-3 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Elongin [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients